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This in-vitro comparative study evaluates the manufacturing accuracy and geometric discrepancy of direct laser sintering (DMLS) versus conventional casting for cobalt-chromium bars in mandibular implant-retained overdentures, demonstrating equivalent precision and fit between both techniques.
A new murine study suggests that sequential therapy with romosozumab followed by denosumab significantly impairs tooth extraction socket healing and increases the risk of medication-related osteonecrosis of the jaw (MRONJ). This research provides critical warnings for managing high-risk osteoporosis patients.
This study identifies a four-gene signature (HSP90AB1, RHOA, CXCL8, IL1B) in peripheral blood that accurately diagnoses MRONJ. Discover how systemic immunosuppression rather than overt inflammation drives this condition and what it means for future clinical diagnostics and therapies.
Actinic cheilitis is a precursor to lip squamous cell carcinoma. Recent research explores how extracellular matrix remodeling, specifically markers like podoplanin and tenascin-C, signal the critical transition from UV-induced damage to invasive malignancy, offering new diagnostic insights for clinicians.
A cross-sectional study reveals that oral frailty and technophobia are strongly linked to depressive symptoms in older adults with chronic diseases. Addressing these factors, alongside social support, is crucial for holistic geriatric care and improved mental health outcomes in clinical practice.
