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A comprehensive review of polymer engineering solutions for sepsis blood purification, highlighting sorbent design principles, biocompatibility, clinical outcomes, and current limitations in critical care.
A 12-month exercise intervention in CKD patients showed minimal changes in bone turnover markers like PINP and TRAP5b. While physical performance improved, age was the only consistent predictor of bone mineral density and osteoporotic status, highlighting the complexity of bone health in chronic kidney disease.
Diabetic kidney disease (DKD) is a leading cause of renal failure. This article examines the potential of Mitochondrial DNA copy number (mtDNA-CN) as a novel biomarker for DKD, focusing on its diagnostic and prognostic utility across blood and urine specimens and the challenges of clinical translation.
A comprehensive systematic review and meta-analysis highlights that nearly half of all African patients with chronic kidney disease suffer from protein-energy wasting, emphasizing the urgent need for routine nutritional screening and early intervention in clinical practice.
This study presents a novel framework for early intradialytic hypotension prediction by forecasting mean arterial pressure trajectories from sparse early observations, utilizing physiology-based identifiable model subsets to improve hemodialysis outcomes and patient safety.
