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The Central Drugs Standard Control Organisation has granted marketing authorization for Qdenga, marking India's first approved dengue vaccine. Developed by Takeda, this two-dose live-attenuated vaccine offers protection for individuals aged 4 to 60 without requiring prior serological screening.

A multi-center Lancet study reveals over 21% of school-going Indian teenagers face moderate-to-high substance use risk. Geographic, digital, and environmental drivers highlight the urgent need for targeted clinical screening, regulatory enforcement, and peer-led interventions in school settings.

Reports of pediatric deaths due to severe Plasmodium falciparum malaria in Chhattisgarh underscore the urgency of rapid field screening, early parenteral artesunate administration, and intensive supportive care. This review outlines diagnostic protocols, treatment guidelines, and pediatric surveillance strategies.

A study in hospitalized pediatric COVID-19 patients revealed a 50.7% fecal carriage rate of multidrug-resistant Klebsiella pneumoniae, including CRKP and ESBL-KP strains. Colistin susceptibility remained intact, but high co-resistance and biofilm formation highlight the need for enhanced stewardship.

A prospective study from the Barcelona Life Study Cohort shows that prenatal air pollution exposure is associated with increased placental mitochondrial DNA content, reflecting compensatory biogenesis. No significant changes were found in telomere length, and neither biomarker directly mediated birth weight.