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A network meta-analysis evaluates contemporary perioperative systemic therapies for muscle-invasive bladder cancer. Regimens combining immune checkpoint inhibitors and antibody-drug conjugates like enfortumab vedotin-pembrolizumab offer superior survival and response rates compared to gemcitabine-cisplatin.
This study evaluates the prognostic significance of the modified Glasgow Prognostic Score (mGPS) and systemic immune-inflammation index (SII) in patients with metastatic castration-resistant prostate cancer treated with cabazitaxel, identifying them as key predictors for survival.
Male infertility is a growing global health concern. This clinical review examines how airborne pollutants, including particulate matter and microplastics, induce oxidative stress and impair testicular function, leading to reduced sperm quality and hormonal imbalance.
This article reviews recently FDA-approved antibiotics for complicated and resistant UTIs in women, focusing on their pharmacology, clinical evidence, and integration into practice between 2017 and 2026.
The CAPLIFE study investigates the association between occupational exposure to metals like nickel, chromium, and iron with prostate cancer risk. Findings suggest a significant link between these metals and locally advanced or metastatic disease, highlighting the need for better occupational health monitoring.
