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A population-based study from SHIP-TREND reveals that serum folic acid and vitamin B12 levels modulate specific circulating microRNAs involved in cell-cycle regulation, DNA synthesis, erythropoiesis, and pregnancy outcomes, offering novel functional biomarkers for clinical practice.
This case study examines a 56-year-old man who experienced sequential bilateral common carotid artery occlusion. Findings revealed protein C deficiency and a patent foramen ovale (PFO), suggesting paradoxical embolism as the primary cause. This highlights the need for thorough thrombophilia screening.
A multicenter retrospective study involving 107 patients shows that upfront autologous stem cell transplantation (ASCT) significantly improves progression-free and overall survival for advanced-stage extra-nodal NK/T-cell lymphoma (NKTCL) patients who achieve their first complete remission.
This study identifies a four-gene signature (HSP90AB1, RHOA, CXCL8, IL1B) in peripheral blood that accurately diagnoses MRONJ. Discover how systemic immunosuppression rather than overt inflammation drives this condition and what it means for future clinical diagnostics and therapies.
A 19-month-old patient post-HSCT for Hurler syndrome died suddenly from fatal pulmonary air emboli. This case reveals a rare, spontaneous link between pneumatosis intestinalis and vascular gas entry, challenging the typical assumption of iatrogenic causes in complex transplant cases.
