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A review of laparoscopic anti-reflux surgery in connective tissue disorders shows 87% reflux resolution and 93% 5-year satisfaction, with partial fundoplication offering lower dysphagia rates.
Artificial intelligence is revolutionizing clinical trials in adult and pediatric rheumatology. By optimizing study design, patient recruitment, and data analysis, AI-driven tools offer a path toward more efficient and accurate clinical research while navigating complex regulatory and ethical landscapes.
A comparative study on the EPIO program highlights that digital pain self-management interventions are significantly more effective when delivered via blended care models. While standalone apps offer convenience, guided support improves module completion and outcomes, particularly for patients with lower education.
A new murine study suggests that sequential therapy with romosozumab followed by denosumab significantly impairs tooth extraction socket healing and increases the risk of medication-related osteonecrosis of the jaw (MRONJ). This research provides critical warnings for managing high-risk osteoporosis patients.
This study identifies a four-gene signature (HSP90AB1, RHOA, CXCL8, IL1B) in peripheral blood that accurately diagnoses MRONJ. Discover how systemic immunosuppression rather than overt inflammation drives this condition and what it means for future clinical diagnostics and therapies.
